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Damien M Cronier Selected Research

olaratumab

1/2020Pharmacokinetics of doxorubicin following concomitant intravenous administration of olaratumab (IMC-3G3) to patients with advanced soft tissue sarcoma.
1/2019Exposure-response relationship of olaratumab for survival outcomes and safety when combined with doxorubicin in patients with soft tissue sarcoma.
1/2018Population Pharmacokinetic Modeling of Olaratumab, an Anti-PDGFRα Human Monoclonal Antibody, in Patients with Advanced and/or Metastatic Cancer.
1/2017Phase II study of olaratumab with paclitaxel/carboplatin (P/C) or P/C alone in previously untreated advanced NSCLC.
7/2016Olaratumab and doxorubicin versus doxorubicin alone for treatment of soft-tissue sarcoma: an open-label phase 1b and randomised phase 2 trial.

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Damien M Cronier Research Topics

Disease

6Neoplasms (Cancer)
01/2018 - 06/2014
5Sarcoma (Soft Tissue Sarcoma)
01/2020 - 07/2016
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2018 - 01/2016
2Disease Progression
01/2019 - 01/2017
2Glioblastoma (Glioblastoma Multiforme)
01/2018 - 01/2016
2Multiple Myeloma
03/2017 - 12/2016
2Vomiting
07/2016 - 01/2015
2Nausea
07/2016 - 01/2015
2Melanoma (Melanoma, Malignant)
03/2016 - 01/2016
2Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
01/2015 - 03/2012
1Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
01/2018
1Body Weight (Weight, Body)
01/2018
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2017
1Febrile Neutropenia
07/2016
1Neutropenia
07/2016
1Mucositis
07/2016
1Colorectal Neoplasms (Colorectal Cancer)
01/2016
1Breast Neoplasms (Breast Cancer)
01/2016
1Aspiration Pneumonia
01/2015
1Leukemia
06/2014
1Fatigue
03/2012
1Chills
03/2012

Drug/Important Bio-Agent (IBA)

5olaratumabIBA
01/2020 - 07/2016
4Doxorubicin (Adriamycin)FDA LinkGeneric
01/2020 - 07/2016
4abemaciclibIBA
01/2018 - 07/2014
3Monoclonal AntibodiesIBA
01/2018 - 01/2015
2Cyclin-Dependent Kinases (cdk Proteins)IBA
01/2018 - 01/2016
2Bortezomib (Velcade)FDA Link
03/2017 - 12/2016
2tabalumabIBA
03/2017 - 12/2016
2B-Cell Activating FactorIBA
03/2017 - 12/2016
2Biomarkers (Surrogate Marker)IBA
03/2016 - 07/2014
2ocaratuzumabIBA
01/2015 - 03/2012
1Dexamethasone (Maxidex)FDA LinkGeneric
03/2017
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
01/2017
1Growth Factor ReceptorsIBA
07/2016
1AnthracyclinesIBA
07/2016
1VemurafenibIBA
03/2016
1Hormones (Hormone)IBA
01/2016
1Pharmaceutical PreparationsIBA
01/2015
1Cyclin-Dependent Kinase 4IBA
07/2014
1Cytostatic AgentsIBA
07/2014
1Phosphotransferases (Kinase)IBA
06/2014
1N1- (4- (3- isopropyl- 2- methylindazol- 5- yl)pyrimidin- 2- yl)- N4- tetrahydropyran- 4- yl- cyclohexane- 1,4- diamineIBA
06/2014
1Proteins (Proteins, Gene)FDA Link
06/2014

Therapy/Procedure

2Drug Therapy (Chemotherapy)
01/2018 - 07/2016
1Intravenous Administration
01/2020